Molecular Determinants of Gastrointestinal Cancers
نویسندگان
چکیده
منابع مشابه
Overview of Gastrointestinal Cancers
Cancers of the gastrointestinal (GI) tract include those of the esophagus, stomach, colon, rectum, and anus. Risk factors, incidence, prevalence, and prognosis vary for each site. Many of the risk factors are modifiable, and in a significant number of cases, the cancers are preventable with proper screening and curable when detected and treated at an early stage. Esophageal cancer is a treatabl...
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Epigenetic alterations, including DNA methylation, histone modifi cation, loss of genome imprinting, chromatin remodeling and non-coding RNAs, are associated with human carcinogenesis. Among them, DNA methylation is a fundamental epigenetic process to modulate gene expression. In cancer cells, altered DNA methylation includes hypermethylation of site-specifi c CpG island promoter and global DNA...
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ژورنال
عنوان ژورنال: Advances in Oncology
سال: 2021
ISSN: 2666-853X
DOI: 10.1016/j.yao.2021.02.026